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VideoClinical Research

Psilocybin Therapy: From Clinical Trials to Emerging Therapeutic Applications

A broad overview of psilocybin as a therapeutic agent — tracing the arc from Griffiths' 2006 mystical experience study through landmark randomized controlled trials for depression, with a look at the conditions now under active clinical investigation including addiction, OCD, and end-of-life distress.

psilocybintherapyclinical trialsdepressionaddictiontherapeutic applicationspsilocybe cubensis

Source Research Papers

Citations in APA 7 format. All studies were sourced from peer-reviewed journals via Google Scholar. Unfamiliar terms? See the plain-language glossary →

James, E., Robertshaw, T. L., Hoskins, M., & Sessa, B. (2020). Psilocybin occasioned mystical-type experiences. Human Psychopharmacology: Clinical and Experimental, 35(5), e2742. https://doi.org/10.1002/hup.2742

ReviewHow it works
Bottom line

The intensity of the 'mystical' part of a psilocybin session seems to predict how much lasting benefit people get — a sign the experience itself is part of how the therapy works.

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